Beyond warfarin: The advent of new oral anticoagulants

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New oral anticoagulants: One Step Closer to Replacing Warfarin

Anticoagulants are widely used for the prevention and treatment of venous and arterial thrombosis. The main indications for long-term anticoagulation therapy include treatment of venous thromboembolism (VTE), stroke prevention in atrial fibrillation (AF) and the prevention of valve thrombosis in patients with mechanical heart valves. For the past 65 years, vitamin K antagonists (VKA), such as w...

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Beyond warfarin: the new generation of oral anticoagulants and their implications for the management of dental patients.

Warfarin has been the primary anticoagulant drug used in the USA for more than 50 years. However, 2 novel types of oral anticoagulants have recently been approved for use in the USA. These are direct thrombin inhibitors (e.g., dabigatran etexilate) and factor Xa inhibitors (e.g., rivaroxaban). Dental health care providers may soon encounter patients who are being prescribed these medications. T...

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The new oral anticoagulants.

Although their first application in clinical practice occurred in the 1940s, vitamin K antagonists remain the only form of oral anticoagulant medication approved for long-term use. Although the available vitamin K antagonists are highly effective for the prevention and/or treatment of most thrombotic disease, the significant interpatient and intrapatient variability in dose-response, the narrow...

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Novel oral anticoagulants and the 73rd anniversary of historical warfarin.

The last 70 years of Warfarin use has been associated with extreme problems. The Novel Oral Anticoagulants (NOACs) are not well utilized in patients with Atrial Fibrillation (AF). We thought to excavate the clinical utility of NOACs and provide some insights into their usefulness as suitable alternatives to Warfarin. Methods: The main objective is to raise awareness of clinicians regarding the ...

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ژورنال

عنوان ژورنال: Indian Journal of Radiology and Imaging

سال: 2015

ISSN: 0971-3026

DOI: 10.4103/0971-3026.169459